This handy checklist of things a traveler might want to bring on an overnight train trip seems to be aimed at women, as it includes blouses, lingerie, and manicure needs, but not shirts or a shaving kit. Regardless of gender, most travelers would probably not pay much attention to the locomotive on the cover.
Railfans, however, will ask what vintage of locomotive the cover is supposed to represent. The nose looks like a General Motors E6, but the porthole pattern on the side belongs solely to the GM E2. The E2s were replaced by E6s in 1940, so this checklist probably comes from about that year.